Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 7/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24189182 | 0.85 | HTR2A (0.59) | FFAR1GPR84HTR2AHTR2BHTR2C | |
| SCHEMBL28167758 | 0.82 | HTR2A (0.60) | HTR2AHTR2BHTR2CHTR6HTR1A | |
| SCHEMBL8959984 | 0.79 | GPR84 (0.55) | GPR84HTR2AHTR2BHTR2CHTR6 | |
| SCHEMBL28337297 | 0.78 | NR4A2 (0.55) | GPR84HTR2AHTR2BHTR2CHTR6 | |
| SCHEMBL30089577 | 0.78 | HTR2A (0.50) | HTR2AHTR2BHTR2CHTR6HTR1A | |
| SCHEMBL27595952 | 0.77 | FFAR1 (0.49) | FFAR1GPR84HTR2AHTR2BHTR2C | |
| SCHEMBL8959677 | 0.75 | HTR1A (0.41) | GPR84HTR2AHTR2BHTR2CHTR6 | |
| SCHEMBL27772016 | 0.75 | FFAR1 (0.43) | FFAR1GPR84HTR2AHTR2BHTR2C | |
| SCHEMBL12120939 | 0.75 | GPR84 (0.58) | FFAR1GPR84HTR2AHTR2BHTR2C | |
| SCHEMBL788913 | 0.72 | HTR2A (0.57) | GPR84HTR2AHTR2BHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957254-B | A kind of 3- alkoxyalkyl indole derivatives and its preparation method and application | 郑州大学 | 2019-11-15 | — | — | CN | disclosed |
| CN-106957254-A | A kind of 3 alkoxyalkyl indole derivativeses and its preparation method and application | 郑州大学 | 2017-07-18 | — | — | CN | disclosed |