Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 4/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609044 | 1.00 | KDM4E (0.36) | KDM4EHPGDALDH1A1HTTBACE1 | |
| SCHEMBL31003034 | 0.82 | PSMB5 (0.48) | ALDH1A1BACE1PSMB5MMP8REN | |
| SCHEMBL939400 | 0.74 | LMNA (0.45) | HPGDALDH1A1PSMB5MMP8REN | |
| SCHEMBL16569135 | 0.74 | LMNA (0.45) | HPGDALDH1A1PSMB5MMP8REN | |
| SCHEMBL5494415 | 0.71 | HPGD (0.38) | HPGDBACE1PSMB5RENANPEP | |
| SCHEMBL31692789 | 0.71 | CACNA2D1 (0.40) | — | |
| SCHEMBL29885722 | 0.70 | CACNA2D1 (0.42) | ALDH1A1 | |
| SCHEMBL31633387 | 0.70 | METAP2 (0.41) | HTTPSMB5RENANPEPLAP3 | |
| SCHEMBL5843971 | 0.70 | ALDH1A1 (0.42) | KDM4EHPGDALDH1A1MMP8RCE1 | |
| SCHEMBL9193585 | 0.70 | LMNA (0.38) | KDM4EALDH1A1BACE1RENANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516369-A | Pyridinone diketo acids: inhibitors of HIV replication in combination therapy | UNIV GEORGIA (US) | 2009-08-26 | — | — | CN | disclosed |