Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 16/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778693 | 0.94 | ACHE (0.41) | ACHEMTNR1AFFAR4 | |
| SCHEMBL2776739 | 0.93 | ACHE (0.44) | ACHE | |
| SCHEMBL2776959 | 0.85 | ALDH1A1 (0.42) | ACHEFFAR4 | |
| SCHEMBL2776619 | 0.83 | ACHE (0.39) | ACHELSS | |
| SCHEMBL2776745 | 0.79 | ALDH1A1 (0.41) | ACHE | |
| SCHEMBL2778160 | 0.78 | ACHE (0.35) | ACHE | |
| SCHEMBL2776698 | 0.76 | MTNR1A (0.35) | MTNR1AFFAR4 | |
| SCHEMBL2780371 | 0.74 | MTNR1A (0.38) | ACHEMTNR1AFFAR4 | |
| SCHEMBL2781327 | 0.74 | NR1H2 (0.36) | ACHEMTNR1AFFAR4 | |
| SCHEMBL2776821 | 0.74 | ACHE (0.36) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139886-A1 | QUINOLONE AND TETRAHYDROQUINOLINE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | Neuraxon Inc. (CA) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116308-A1 | QUINOLONE AND TETRAHYDROQUINOLINE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2008-10-02 | — | — | WO | disclosed |