Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795799 | 0.86 | TSHR (0.43) | HSD11B1NR1H4RENCETPHTR2C | |
| SCHEMBL27774898 | 0.85 | ENPP2 (0.34) | NR1H4ENPP2RENGHSRMAPT | |
| SCHEMBL27795796 | 0.83 | SLC22A12 (0.38) | KDM1AHDAC8HDAC6HSD11B1NR1H4 | |
| SCHEMBL13132300 | 0.78 | REN (0.40) | HSD11B1NR1H4RENHTR2CSLC6A4 | |
| SCHEMBL13132277 | 0.77 | REN (0.46) | HSD11B1NR1H4REN | |
| SCHEMBL2834678 | 0.77 | REN (0.49) | HSD11B1NR1H4REN | |
| SCHEMBL13132274 | 0.76 | REN (0.41) | NR1H4REN | |
| SCHEMBL18509080 | 0.76 | HSD11B1 (0.39) | HSD11B1NR1H4RENCETPHTR2C | |
| SCHEMBL2810132 | 0.75 | REN (0.41) | NR1H4REN | |
| SCHEMBL18509079 | 0.74 | REN (0.40) | HSD11B1NR1H4RENCETPHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |