Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813706 | 0.78 | MAPT (0.51) | ACHERAB9AMAPTALDH1A1LMNA | |
| SCHEMBL28791442 | 0.76 | ALDH1A1 (0.54) | ACHERAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL27391395 | 0.76 | CYP3A4 (0.46) | ACHERAB9AALDH1A1NPC1BCHE | |
| SCHEMBL27925402 | 0.76 | MAOB (0.45) | ACHERAB9AMAPTKDM4EBCHE | |
| SCHEMBL28032033 | 0.72 | ACHE (0.44) | ACHERAB9AMAPTALDH1A1LMNA | |
| SCHEMBL4016329 | 0.72 | TDP1 (0.42) | ACHERAB9AMAPTALDH1A1LMNA | |
| SCHEMBL14342967 | 0.71 | ALDH1A1 (0.60) | RAB9AMAPTALDH1A1LMNANPC1 | |
| SCHEMBL4573467 | 0.71 | ACHE (0.41) | ACHEBCHENR1H4 | |
| SCHEMBL27741407 | 0.71 | ACHE (0.50) | ACHEALDH1A1BCHE | |
| SCHEMBL3978167 | 0.71 | RAB9A (0.52) | RAB9AMAPTALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522184-A | Thiourea compounds | NAT HEALTH RESEARCH INSTITUTES (CN) | 2009-09-02 | — | — | CN | disclosed |