Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667210 | 0.90 | GGT1 (0.42) | GPR142SIGMAR1KMT2AHPGDNPC1 | |
| SCHEMBL1667207 | 0.90 | GGT1 (0.42) | GPR142SIGMAR1KMT2AHPGDNPC1 | |
| SCHEMBL6384640 | 0.88 | MC5R (0.39) | GPR142ELANE | |
| SCHEMBL7281103 | 0.83 | PARP1 (0.50) | PARP1ERAP2LNPEPERAP1HPGD | |
| SCHEMBL7314276 | 0.81 | ERAP2 (0.36) | ERAP2LNPEPERAP1ELANEIL1RN | |
| Imidazole SCHEMBL27889109 | 0.81 | GPR142 (0.39) | GPR142SIGMAR1KMT2AHPGDNPC1 | |
| SCHEMBL9238392 | 0.79 | GGT1 (0.47) | GPR142 | |
| SCHEMBL27506310 | 0.79 | CTSL (0.51) | — | |
| Hydrochloric Acid SCHEMBL8616629 | 0.79 | KMT2A (0.52) | GPR142SIGMAR1KMT2AELANE | |
| SCHEMBL23573011 | 0.78 | NLN (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | claimed |
| CN-101531637-B | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GUANGZHOU INST OF BIOMEDICINE AND HEALTH | 2011-07-13 | — | — | CN | disclosed |
| CN-101531637-A | A novel compound capable of restraining and blocking M2 ion channel activity and application thereof | CHINESE ACADEMY OF SCIENCES GU | 2009-09-16 | — | — | CN | disclosed |