Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239495 | 0.87 | SMN1; SMN2 (0.43) | ACECTSSCTSKCTSL | |
| SCHEMBL1667207 | 0.86 | GGT1 (0.42) | GGT1MMEACEGPR142 | |
| SCHEMBL1667210 | 0.86 | GGT1 (0.42) | GGT1MMEACEGPR142 | |
| SCHEMBL5870219 | 0.82 | MME (0.59) | MMEACECPA1ACE2 | |
| SCHEMBL8249923 | 0.82 | MME (0.59) | MMEACECPA1ACE2 | |
| SCHEMBL9237438 | 0.82 | MASP2 (0.40) | — | |
| SCHEMBL27776883 | 0.79 | GPR142 (0.39) | GPR142 | |
| SCHEMBL7622435 | 0.78 | CTSC (0.42) | CTSSCTSK | |
| SCHEMBL3217867 | 0.78 | CTSC (0.42) | CTSSCTSK | |
| SCHEMBL5870183 | 0.78 | CPB2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675112-A1 | Imidazole-containing inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-10-04 | — | — | EP | disclosed |