Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790488 | 0.79 | CYP2D6 (0.44) | ADRA2AADRA1AADRA1DADRA1BCYP2D6 | |
| SCHEMBL2778150 | 0.78 | NISCH (0.48) | ADRA2AADRA1ANISCHCYP2D6HTR1A | |
| SCHEMBL2776285 | 0.77 | ADRA1A (0.54) | ADRA2AADRA1AADRA1DADRA1BCYP2D6 | |
| SCHEMBL769114 | 0.71 | NISCH (0.56) | ADRA2AADRA1AADRA1DADRA1BNISCH | |
| SCHEMBL9814102 | 0.70 | ADRA1A (0.48) | ADRA2AADRA1ACYP2D6HTR1AOPRM1 | |
| Hydrochloric Acid SCHEMBL10749865 | 0.69 | CYP2D6 (0.59) | ADRA2AADRA1ACYP2D6HTR1AOPRM1 | |
| SCHEMBL2777989 | 0.69 | MEN1 (0.34) | ADRA2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10747744 | 0.69 | CYP2D6 (0.49) | ADRA2AADRA1ACYP2D6HTR1AOPRM1 | |
| SCHEMBL10851796 | 0.69 | ADRA2A (0.41) | ADRA2AADRA1AADRA1DADRA1BCYP2D6 | |
| SCHEMBL16865524 | 0.69 | HTR2A (0.37) | HTR2AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| US-20050143418-A1 | Pesticidal heterocycles | FMC CORPORATION | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | ADRA2A 1935/4885ADRA1A 1130/4885ADRA1D 1129/4885 |
| US-20050143418-A1 | Pesticidal heterocycles | DDT, TRHR, ACHE | ADRA2A 1884/4885ADRA1A 974/4885ADRA1D 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.