Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044733 | 0.77 | ENPP2 (0.39) | HTR1AAPPSRD5A1SRD5A2 | |
| SCHEMBL7827220 | 0.76 | PDGFRB (0.59) | HDAC8MAOBALOX5ABCB1HTR1A | |
| SCHEMBL2990559 | 0.73 | KDM4E (0.57) | HDAC8MAOBFLT3CTSLAPP | |
| SCHEMBL29375765 | 0.73 | KDM4E (0.57) | HDAC8MAOBFLT3CTSLAPP | |
| SCHEMBL2992089 | 0.72 | MAOB (0.53) | HDAC8MAOBFLT3ALOX5ABCB1 | |
| SCHEMBL30461777 | 0.72 | MAOB (0.53) | HDAC8MAOBFLT3ALOX5ABCB1 | |
| SCHEMBL21436935 | 0.72 | HDAC8 (0.51) | HDAC8MAOBABCB1HTR1ADRD2 | |
| SCHEMBL27960499 | 0.71 | ALOX5 (0.48) | MAOBALOX5MTNR1ASRD5A2 | |
| SCHEMBL8204838 | 0.71 | HDAC8 (0.53) | HDAC8MAOBFLT3CTSLAPP | |
| SCHEMBL19612478 | 0.70 | ALOX5 (0.65) | MAOBFLT3ALOX5PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105520943-A | Anti-diabetics oral pharmaceutical composition | ZHU ZHONGLIANG | 2016-04-27 | — | — | CN | disclosed |
| CN-105434434-A | Antidiabetic oral drug composition | ZHU ZHONGLIANG | 2016-03-30 | — | — | CN | disclosed |
| CN-105434433-A | Antidiabetic oral drug composition | ZHU ZHONGLIANG | 2016-03-30 | — | — | CN | disclosed |
| CN-105412095-A | Anti-diabetes oral drug composition | ZHU ZHONGLIANG | 2016-03-23 | — | — | CN | disclosed |
| CN-105287535-A | Anti-diabetes oral pharmaceutical composition | ZHU ZHONGLIANG | 2016-02-03 | — | — | CN | disclosed |
| CN-105232546-A | Anti-diabetic oral drug composition | ZHU ZHONGLIANG | 2016-01-13 | — | — | CN | disclosed |
| CN-105232552-A | Anti-diabetic oral drug composition | ZHU ZHONGLIANG | 2016-01-13 | — | — | CN | disclosed |
| CN-105213384-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213379-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213382-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213385-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213387-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213381-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105213383-A | A kind of diabetes combination of oral medication | ZHU ZHONGLIANG | 2016-01-06 | — | — | CN | disclosed |
| CN-105193797-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |
| CN-105193796-A | Diabetes mellitus resistant oral medicine composition | ZHU ZHONGLIANG | 2015-12-30 | — | — | CN | disclosed |
| CN-101687828-A | Thiadiazole derivatives as antidiabetic agents | NOVARTIS AG | 2010-03-31 | — | — | CN | disclosed |