Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493949 | 0.78 | ENPP2 (0.42) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL27779362 | 0.77 | HDAC8 (0.44) | APPSRD5A1SRD5A2HTR1A | |
| SCHEMBL2077679 | 0.76 | SRD5A1 (0.49) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL186995 | 0.74 | STAT3 (0.48) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL27607579 | 0.73 | CYP2A6 (0.44) | ENPP2MAPTBACE1NPC1MAPK14 | |
| SCHEMBL14252834 | 0.72 | L3MBTL1 (0.44) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL18593225 | 0.72 | SMN1; SMN2 (0.44) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL188066 | 0.72 | L3MBTL1 (0.50) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| SCHEMBL1997971 | 0.72 | GPR84 (0.50) | ENPP2L3MBTL1NSD2ABL1PPARG | |
| Ethoxycarbonyl Group SCHEMBL27745996 | 0.71 | BACE1 (0.39) | ENPP2L3MBTL1NSD2ABL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073730-A | monocyclic pyridine derivatives | WEI CAIR | 2015-11-18 | — | — | CN | disclosed |