Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27800586 | 0.99 | EGFR (0.30) | EGFRGAA | |
| Hydrochloric Acid SCHEMBL27779273 | 0.81 | MEN1 (0.41) | GAA | |
| Hydrochloric Acid SCHEMBL27800632 | 0.80 | HTR6 (0.41) | GAA | |
| Hydrochloric Acid SCHEMBL27779214 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27800625 | 0.76 | TP53 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL27779691 | 0.75 | UHRF1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL27779402 | 0.75 | KDM4E (0.45) | GAA | |
| SCHEMBL19705565 | 0.74 | HTR2C (0.33) | — | |
| Hydrochloric Acid SCHEMBL27779136 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL10025680 | 0.72 | ADRB1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101641360-A | Piperazine derivatives, preparation method and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2010-02-03 | — | — | CN | disclosed |