Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL17199766 | 0.81 | TSHR (0.33) | TDP1TSHR | |
| SCHEMBL20122295 | 0.79 | LMNA (0.46) | TDP1TSHRLMNA | |
| Propylene Glycol SCHEMBL7522896 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL3535 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL15864609 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1MAPK1LMNA | |
| Propylene Glycol SCHEMBL28578 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1MAPK1LMNA | |
| SCHEMBL161500 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1 | |
| Propylene Glycol SCHEMBL55583 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646718-B | Curable resin composition, protective film, and method for forming protective film | JSR CORP JP | 2013-04-03 | — | — | CN | disclosed |
| CN-102898149-A | Solvent or solvent composition for manufacturing laminated ceramic member | DAICEL CHEM | 2013-01-30 | — | — | CN | disclosed |
| CN-101646718-A | The formation method of curable resin composition, protective membrane and protective membrane | JSR CORP JP | 2010-02-10 | — | — | CN | disclosed |