Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
| ▸ | CCND2 | P30279 | 2/20 | 0.32 |
| ▸ | CCND3 | P30281 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780894 | 0.88 | HTR2A (0.37) | HTR2AHTR2CMAPTMAT2ACYP11B1 | |
| SCHEMBL28799118 | 0.82 | HTR2A (0.36) | HTR2AHTR2CMAPTMAT2ACDK4 | |
| SCHEMBL28779598 | 0.78 | HTR2C (0.36) | HTR2AHTR2CMAT2AATMCDC7 | |
| SCHEMBL28799146 | 0.71 | HTR2A (0.36) | HTR2AHTR2CMAPTCYP11B1CYP11B2 | |
| SCHEMBL27780825 | 0.71 | PLK1 (0.40) | HTR2AHTR2CMAPTCYP11B1CYP11B2 | |
| SCHEMBL23549006 | 0.69 | MAT2A (0.54) | MAPTMAT2ACDK4CCND1CCND2 | |
| SCHEMBL30894482 | 0.69 | MAT2A (0.54) | MAPTMAT2ACDK4CCND1CCND2 | |
| SCHEMBL29093852 | 0.69 | HTR2A (0.35) | HTR2AHTR2CMAPTCDK4CCND1 | |
| SCHEMBL29093832 | 0.67 | HTR2A (0.34) | HTR2AHTR2CMAPTCDK4CCND1 | |
| SCHEMBL30095703 | 0.64 | KDM4E (0.42) | HTR2AHTR2CMAPTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |