Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780826 | 0.78 | HTR2A (0.37) | HTR2CHTR2AATMMAT2ACDC7 | |
| SCHEMBL3263915 | 0.73 | BRPF1 (0.57) | HTR2CHTR2AATMBRPF1CA12 | |
| SCHEMBL14320197 | 0.69 | BTK (0.46) | HTR2CHTR2AHDAC1HDAC6KDM4E | |
| SCHEMBL17637285 | 0.69 | HTR2C (0.37) | HTR2CHTR2AATMBRPF1CA12 | |
| SCHEMBL18544278 | 0.69 | HTR2C (0.37) | HTR2CHTR2AATMBRPF1CA12 | |
| SCHEMBL27780894 | 0.69 | HTR2A (0.37) | HTR2CHTR2AKDM4EALDH1A1HPGD | |
| SCHEMBL3839835 | 0.67 | HDAC1 (0.43) | HTR2CHTR2ABRD4HDAC1HDAC6 | |
| SCHEMBL18544253 | 0.67 | HTR2C (0.42) | HTR2CHTR2AATMBRPF1CA12 | |
| SCHEMBL28779597 | 0.67 | HDAC1 (0.43) | HTR2CHTR2AATMBRPF1CA12 | |
| SCHEMBL17637279 | 0.67 | HDAC1 (0.45) | HTR2CHTR2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |