Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27780825 | 0.88 | PLK1 (0.40) | PLK1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL29094005 | 0.83 | HTR2A (0.35) | PLK1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL9540156 | 0.78 | POLB (0.45) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL28799146 | 0.74 | HTR2A (0.36) | PLK1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL13640280 | 0.73 | ALDH1A1 (0.54) | PLK1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL30095703 | 0.73 | KDM4E (0.42) | PLK1ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL20616492 | 0.72 | BRPF1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20616495 | 0.72 | BRPF1 (0.39) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL29093852 | 0.71 | HTR2A (0.35) | MAPTHTR2AHTR2CSRCLYN | |
| SCHEMBL20616475 | 0.71 | BRPF1 (0.38) | ALDH1A1MAPTSRCBTKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |