Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174281 | 0.83 | PKM (0.36) | PKMNPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL28281023 | 0.74 | TRPM8 (0.32) | — | |
| SCHEMBL20252572 | 0.72 | SCN8A (0.34) | NPC1RAB9ACYP2C9CYP2C19NPSR1 | |
| SCHEMBL28781892 | 0.71 | MEN1 (0.34) | MAPTPOLBALDH1A1KMT2A | |
| SCHEMBL28950613 | 0.70 | NPC1 (0.49) | PKMNPC1RAB9ACYP2C9CYP2C19 | |
| SCHEMBL3804334 | 0.69 | GRM5 (0.33) | KMT2A | |
| SCHEMBL28337730 | 0.68 | FAAH (0.34) | ALDH1A1 | |
| SCHEMBL27838787 | 0.68 | POLB (0.38) | NPC1RAB9AMAPTPOLBGAA | |
| SCHEMBL28335538 | 0.68 | PAX8 (0.32) | — | |
| SCHEMBL8126885 | 0.68 | POLB (0.47) | NPC1RAB9ANPSR1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101720325-B | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections | MICURX PHARMACEUTICALS INC | 2013-04-24 | — | — | CN | disclosed |
| CN-101720325-A | Antimicrobial ortho-fluorophenyl oxazolidinones for treatment of bacterial infections | MICURX PHARMACEUTICALS INC | 2010-06-02 | — | — | CN | disclosed |