Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761075 | 0.86 | ALDH1A1 (0.55) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4354098 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27782793 | 0.82 | MEN1 (0.40) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4351932 | 0.77 | KDM4E (0.41) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL27782797 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4342192 | 0.77 | MAPT (0.53) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4355430 | 0.75 | CNR1 (0.47) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL4350105 | 0.75 | MAPT (0.55) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4354075 | 0.75 | IDO1 (0.46) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4349891 | 0.73 | HTT (0.41) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |