Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65919 | 0.91 | — | — | |
| SCHEMBL3283578 | 0.73 | — | — | |
| SCHEMBL134463 | 0.72 | — | — | |
| SCHEMBL216358 | 0.71 | — | — | |
| SCHEMBL15031 | 0.71 | CALM1 (0.32) | — | |
| SCHEMBL309768 | 0.70 | MAOA (0.40) | LOXL2 | |
| SCHEMBL2139341 | 0.68 | — | — | |
| SCHEMBL933763 | 0.68 | — | — | |
| SCHEMBL17730 | 0.68 | — | — | |
| SCHEMBL3581330 | 0.68 | MAOA (0.48) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778831-B | piperazine amide derivatives | HOFFMANN LA ROCHE | 2014-08-20 | — | — | CN | disclosed |
| CN-103772299-A | Novel piperazine amide derivatives | HOFFMANN LA ROCHE | 2014-05-07 | — | — | CN | disclosed |
| CN-101778831-A | Novel piperazine amide derivatives | HOFFMANN LA ROCHE | 2010-07-14 | — | — | CN | disclosed |