SCHEMBL309768

SCHEMBL309768

NCCCc1[c]cccc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
SIGMAR1 Q99720 2/20 0.35
HTR2A P28223 3/20 0.34
CYP2A6 P11509 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
HRH1 P35367 2/20 0.34
KIF11 P52732 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3581330 0.94 MAOA (0.48) MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2
SCHEMBL3589419 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3584588 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3584831 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3593183 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3587599 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3588310 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3596268 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3587172 0.92 MAOA (0.47) MAOASIGMAR1HRH1
SCHEMBL3593093 0.92 MAOA (0.47) MAOASIGMAR1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024031596-A1 COMPOSITION FOR TREATING KERATIN FIBERS L'OREAL (FR) 2024-02-15 WO claimed
US-20230174509-A1 THERAPEUTIC USE OF PLEUROMUTILINS ARIVA MED GMBH (AT) 2023-06-08 US claimed
EP-4188316-A1 HAIR COSMETIC COMPOSITIONS FOR PRESERVING OR MAINTAINING THE STYLE OR SHAPE OF HAIR L'OREAL (FR) 2023-06-07 EP claimed
EP-4135683-A1 THERAPEUTIC USE OF PLEUROMUTILINS Nabriva Therapeutics GMBH (AT) 2023-02-22 EP claimed
CN-115413238-A Therapeutic use of pleuromutilin compounds 纳布里瓦治疗有限责任公司 2022-11-29 CN claimed
WO-2022146720-A1 COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS L'OREAL (FR) 2022-07-07 WO claimed
CN-114685968-A Damp-heat-resistant polycarbonate composition and preparation method and application thereof 金发科技股份有限公司 2022-07-01 CN claimed
US-20220202686-A1 COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS L'OREAL (FR) 2022-06-30 US claimed
US-20220202674-A1 COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS L'OREAL (FR) 2022-06-30 US claimed
WO-2022026790-A1 HAIR COSMETIC COMPOSITIONS FOR PRESERVING OR MAINTAINING THE STYLE OR SHAPE OF HAIR L'OREAL (FR) 2022-02-03 WO claimed
WO-2006065511-A2 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PRODUCTS, INC. (US) 2006-06-22 WO claimed
US-20060128883-A1 Aesthetic, stable chromatic emulsions AVON PRODUCTS, INC. 2006-06-15 US claimed
CN-1281362-A Novel combination medicine ASTRA ZENECA BRITISH CO LTD (GB) 2001-01-24 CN claimed
EP-1027052-A1 NOVEL COMBINATION AstraZeneca UK Limited (GB) 2000-08-16 EP claimed
US-6063789-A Aminoisoquinolines and aminotheinopyridine derivatives and their use as anti-inflammatory agents ASTRA PHARMACEUTICALS, LTD. (GB) 2000-05-16 US claimed
US-6046191-A PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND AN AMIDINE COMPOUND; FOR TREATMENT OF INFLAMMATORY DISORDERS ASTRA PHARMACEUTICALS LTD. (GB) 2000-04-04 US claimed
CN-1221407-A Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents ASTRA PHARMA PROD (GB) 1999-06-30 CN claimed
WO-1999018960-A1 NOVEL COMBINATION ASTRAZENECA UK LIMITED (GB) 1999-04-22 WO claimed
EP-0892784-A1 AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS Astra Pharmaceuticals Limited (GB) 1999-01-27 EP claimed
WO-1997038977-A1 AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS ASTRA PHARMACEUTICALS LTD. (GB) 1997-10-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220202686-A1 COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS CUTA, SGMS1, PHOSPHO1 MAOA 2918/4885SIGMAR1 1107/4885HTR2A 2328/4885
US-20220202674-A1 COSMETIC AND PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SURFACTANTS AND ANIONIC COMPOUNDS SGMS1, MITF, SGMS2 MAOA 3519/4885SIGMAR1 2151/4885HTR2A 3515/4885
US-20230174509-A1 THERAPEUTIC USE OF PLEUROMUTILINS MLN, PLEC, PELP1 MAOA 1431/4885SIGMAR1 3062/4885HTR2A 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.