Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807412 | 0.84 | HTR6 (0.52) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27807290 | 0.84 | CYP2C19 (0.62) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27750197 | 0.80 | HTR6 (0.50) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL1354653 | 0.79 | HTT (0.60) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Methylphenylsulfone SCHEMBL27814592 | 0.77 | LMNA (0.39) | LMNAL3MBTL1TDP1AKR1C3AKR1C1 | |
| SCHEMBL29558135 | 0.76 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL429849 | 0.76 | HTR6 (1.00) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28781691 | 0.76 | HTR6 (0.46) | HTR6HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27642789 | 0.75 | HTR6 (0.60) | HTR6HTTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28794299 | 0.75 | HTR6 (0.96) | HTR6HTTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759628-B | Ethynylindole compounds | ONO PHARMACEUTICAL CO | 2013-02-27 | — | — | CN | disclosed |
| CN-101759628-A | Ethynylindole compounds | ONO PHARMACEUTICAL CO | 2010-06-30 | — | — | CN | disclosed |