Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354690 | 0.80 | HTT (0.60) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL1357381 | 0.79 | HTT (0.63) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL27785348 | 0.79 | HTR6 (0.58) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL675296 | 0.77 | HTT (0.65) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL6357944 | 0.77 | HTR6 (0.68) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL4862697 | 0.76 | HTT (1.00) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL3972209 | 0.76 | HTR6 (0.70) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL29558135 | 0.75 | HTR6 (1.00) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL429849 | 0.75 | HTR6 (1.00) | HTTL3MBTL1MEN1KMT2APKM | |
| SCHEMBL21968893 | 0.75 | FABP4 (0.71) | HTTL3MBTL1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318725-B2 | Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-11-27 | — | — | US | disclosed |
| US-20110281849-A1 | Aryl Indolyl Sulfonamide Compounds and Their Use as 5-HT6 Ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-11-17 | — | — | US | disclosed |
| WO-2010032257-A1 | ARYL INDOLYL SULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281849-A1 | Aryl Indolyl Sulfonamide Compounds and Their Use as 5-HT6 Ligands | HTR6, HTR1A, HTR2C | HTT 157/4885L3MBTL1 4599/4885MEN1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.