Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 3/20 | 0.32 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206704 | 0.69 | KDM4E (0.46) | MAPTKDM4ETOP2ATOP2BTSHR | |
| SCHEMBL28343693 | 0.62 | L3MBTL1 (0.53) | MAPTTSHRHRH3HRH4ALDH1A1 | |
| SCHEMBL28132575 | 0.62 | ALDH1A1 (0.43) | MAPTKDM4ETSHRPNPHRH3 | |
| SCHEMBL31081656 | 0.62 | KDM4E (0.49) | MAPTKDM4EHRH3HRH4ALDH1A1 | |
| SCHEMBL21142100 | 0.62 | KDM4E (0.49) | MAPTKDM4EHRH3HRH4ALDH1A1 | |
| SCHEMBL27694256 | 0.61 | L3MBTL1 (0.46) | MAPTKDM4ETSHRKMT2AMEN1 | |
| SCHEMBL764538 | 0.60 | GRM5 (0.49) | HRH3HRH4ALDH1A1ASIC3 | |
| SCHEMBL21142103 | 0.60 | KDM4E (0.48) | MAPTKDM4EHRH3HRH4ALDH1A1 | |
| SCHEMBL14750985 | 0.60 | ASIC3 (0.51) | MAPTKDM4EKMT2AHRH3HRH4 | |
| SCHEMBL18738906 | 0.60 | KDM4E (0.50) | MAPTKDM4EKMT2AHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600715-A | Compound with angiotensin-ii receptor antagonistic action and PPAR γ activating activities | PFIZER PROD INC (US) | 2009-12-09 | — | — | CN | disclosed |