SCHEMBL27786276

SCHEMBL27786276

CCCCc1nc(CC)[nH]c1Cl

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TYMP P19971 4/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
GSK3B P49841 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
PARP1 P09874 1/20 0.32
DDAH1 O94760 1/20 0.32
CRHR1 P34998 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3103281 0.80 TYMP (0.39) TYMPGAAALDH1A1MAPK1L3MBTL1
SCHEMBL28882429 0.78 ALDH1A1 (0.37) GAAALDH1A1MAPK1ADORA3ADORA2A
SCHEMBL27807973 0.78 TYMP (0.42) TYMPALDH1A1MAPK1L3MBTL1GSK3B
SCHEMBL3205670 0.78 ALDH1A1 (0.41) TYMPALDH1A1MAPK1GSK3BPARP1
SCHEMBL13384270 0.75 ALDH1A1 (0.39) TYMPALDH1A1MAPK1GSK3BPARP1
SCHEMBL7275316 0.73 ALDH1A1 (0.44) ALDH1A1MAPK1PARP1HSD17B10
SCHEMBL7626256 0.72 ALDH1A1 (0.46) TYMPALDH1A1MAPK1GSK3BPARP1
SCHEMBL11226357 0.72 GPR84 (0.42) ALDH1A1ADORA3ADORA2AADORA1
SCHEMBL14743462 0.71 ALDH1A1 (0.44) TYMPALDH1A1MAPK1PARP1
SCHEMBL13891112 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101780949-B Method for preparing multi-walled carbon nano-tube INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2011-12-07 CN disclosed
CN-101780949-A Method for preparing multi-walled carbon nano-tube CHINESE ACAD INST CHEMISTRY 2010-07-21 CN disclosed