Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807973 | 0.82 | TYMP (0.42) | TYMPL3MBTL1ALDH1A1HRH3MAPK1 | |
| SCHEMBL27786276 | 0.80 | TYMP (0.37) | TYMPL3MBTL1ALDH1A1HRH3MAPK1 | |
| SCHEMBL8025094 | 0.78 | — | — | |
| SCHEMBL3205670 | 0.69 | ALDH1A1 (0.41) | TYMPALDH1A1MAPK1GSK3B | |
| SCHEMBL6123017 | 0.69 | TYMP (0.38) | TYMPL3MBTL1ALDH1A1MAPK1TSHR | |
| SCHEMBL5138095 | 0.69 | HRH3 (0.41) | L3MBTL1ALDH1A1HRH3MAPK1TSHR | |
| SCHEMBL13384270 | 0.67 | ALDH1A1 (0.39) | TYMPALDH1A1MAPK1GSK3B | |
| SCHEMBL5276816 | 0.67 | HCAR2 (0.37) | TYMPL3MBTL1ALDH1A1HRH3MAPK1 | |
| SCHEMBL7626256 | 0.67 | ALDH1A1 (0.46) | TYMPALDH1A1MAPK1GSK3B | |
| SCHEMBL11386954 | 0.66 | SLC5A2 (0.33) | L3MBTL1ALDH1A1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141151-B1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEM (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-2141151-A1 | METHOD FOR PRODUCING 2-HALOIMIDAZOLE COMPOUND | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-01-06 | — | — | EP | disclosed |