Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808348 | 0.80 | GPR119 (0.40) | GPR119MAPTTP53RAB9A | |
| SCHEMBL27808321 | 0.80 | GPR119 (0.40) | GPR119MAPTTP53RAB9A | |
| SCHEMBL27786472 | 0.79 | PDK2 (0.35) | HRH3KCNH2GPR119ALDH1A1USP30 | |
| SCHEMBL27808281 | 0.75 | PTAFR (0.41) | HRH3RAB9ASMN1; SMN2 | |
| SCHEMBL3665747 | 0.74 | HRH3 (0.62) | HRH3KCNH2GPR119MGLLTP53 | |
| SCHEMBL3665742 | 0.74 | HRH3 (0.62) | HRH3KCNH2GPR119MGLLTP53 | |
| SCHEMBL3636321 | 0.74 | HRH3 (0.65) | HRH3KCNH2GPR119MAPTMGLL | |
| Hydrochloric Acid SCHEMBL3639931 | 0.73 | HRH3 (0.64) | HRH3KCNH2GPR119MAPTMGLL | |
| Tert-Butyl Formate SCHEMBL27786378 | 0.72 | HRH3 (0.55) | HRH3KCNH2GPR119MAPTMGLL | |
| SCHEMBL18924338 | 0.72 | HRH3 (0.70) | HRH3KCNH2GPR119MGLLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |