Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808321 | 1.00 | GPR119 (0.40) | GPR119DRD2HTR2ADRD3MAPT | |
| SCHEMBL27808501 | 0.84 | HDAC1 (0.49) | MAPTRAB9A | |
| SCHEMBL27808326 | 0.84 | HDAC1 (0.49) | MAPTRAB9A | |
| SCHEMBL27786338 | 0.81 | GCG (0.44) | GCGR | |
| SCHEMBL27786384 | 0.80 | HRH3 (0.52) | GPR119MAPTTP53RAB9A | |
| SCHEMBL27808277 | 0.80 | KHK (0.49) | — | |
| SCHEMBL27808402 | 0.79 | RAB9A (0.35) | MAPTRAB9ADGAT2 | |
| SCHEMBL28787442 | 0.74 | HDAC1 (0.52) | — | |
| SCHEMBL28787440 | 0.74 | CRHR1 (0.40) | RAB9A | |
| SCHEMBL27808373 | 0.74 | CRHR1 (0.40) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |