Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949440 | 0.77 | SLC1A3 (0.49) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL4225010 | 0.76 | KIF11 (0.53) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL8619633 | 0.75 | SLC1A2 (0.61) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL3151057 | 0.74 | KIF11 (0.59) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL1464399 | 0.74 | MMP1 (0.54) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL10157181 | 0.73 | CA1 (0.53) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL28200284 | 0.72 | CES2 (0.50) | KIF11CA1CA2CA9CES2 | |
| SCHEMBL1465778 | 0.71 | MMP1 (0.55) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL13833092 | 0.70 | KIF11 (0.47) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL230582 | 0.70 | KIF11 (0.55) | KIF11CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-B | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |