Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031658 | 0.90 | CHRM5 (0.53) | GRIN2BGRIN1CHRM5NPC1RAB9A | |
| SCHEMBL3937409 | 0.89 | CHRM5 (0.47) | GRIN2BGRIN1CHRM5NPC1RAB9A | |
| SCHEMBL27652264 | 0.89 | GRIN2B (0.49) | GRIN2BGRIN1CHRM5NPC1RAB9A | |
| SCHEMBL8324164 | 0.87 | ALDH1A1 (0.51) | GRIN2BGRIN1CHRM5NPC1RAB9A | |
| SCHEMBL17061756 | 0.84 | MAOB (0.44) | GRIN2BGRIN1NPC1RAB9AHPGD | |
| SCHEMBL28688634 | 0.80 | KMT2A (0.48) | CHRM5NPC1RAB9AMAOBCYP1A2 | |
| SCHEMBL27629847 | 0.79 | PNMT (0.43) | GRIN2BGRIN1CHRM5NPC1RAB9A | |
| SCHEMBL69726 | 0.79 | MAOB (0.57) | ALDH1A1HPGDMAOBCYP2C9TAAR1 | |
| SCHEMBL5816057 | 0.78 | CHRM5 (0.44) | GRIN2BGRIN1CHRM5PNMTMAOB | |
| SCHEMBL8196750 | 0.78 | G6PC1 (0.49) | GRIN2BGRIN1SIGMAR1MAOBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572367-C | 1- (azolin-2-yl) amino-1, 2-diphenylethane compounds for controlling insects, arachnids and nematodes | BASF AG (DE) | 2009-12-23 | — | — | CN | disclosed |