Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787064 | 0.82 | MTNR1A (0.52) | CHRM4MTNR1AMTNR1BME3HPGD | |
| Trifluoroacetic Acid SCHEMBL27808896 | 0.81 | MTNR1A (0.55) | CHRM4MTNR1AMTNR1BME3NAMPT | |
| SCHEMBL27787056 | 0.81 | ME3 (0.47) | MTNR1AMTNR1BME3MAOB | |
| SCHEMBL7898002 | 0.76 | ME3 (0.76) | CHRM4ME3HTTRAB9AMAOB | |
| SCHEMBL7899165 | 0.75 | ME3 (0.58) | CHRM4ME3HPGDHTTRAB9A | |
| SCHEMBL9936379 | 0.74 | NPC1 (0.57) | RAB9A | |
| SCHEMBL3637427 | 0.74 | MTNR1A (0.61) | CHRM4MTNR1AMTNR1BME3RAB9A | |
| SCHEMBL17061423 | 0.72 | F10 (0.46) | ME3SLC6A5HPGDHTTMAOB | |
| SCHEMBL32665202 | 0.72 | CKS1B (0.52) | CHRM4ME3HPGDHTTMAOB | |
| SCHEMBL12321963 | 0.71 | CKS1B (0.53) | CHRM4ME3SLC6A5HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101796027-A | N-piperidin-4-ylmethyl-amide derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH AS | 2010-08-04 | — | — | CN | disclosed |