Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.61 |
| ▸ | ME3 | Q16798 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27808896 | 0.92 | MTNR1A (0.55) | MTNR1AMTNR1BME3NAMPTEPHX2 | |
| SCHEMBL12041223 | 0.89 | LMNA (0.58) | MTNR1AMTNR1BME3KMT2ASMN1; SMN2 | |
| SCHEMBL3209065 | 0.88 | ME3 (0.63) | MTNR1AMTNR1BME3EPHX2KMT2A | |
| SCHEMBL9852459 | 0.81 | SIGMAR1 (0.75) | SIGMAR1 | |
| SCHEMBL19658840 | 0.80 | DRD2 (0.65) | MTNR1AMTNR1BME3EPHX2SMN1; SMN2 | |
| SCHEMBL17748966 | 0.80 | EPHX2 (0.61) | ME3EPHX2KMT2ASMN1; SMN2NPY5R | |
| SCHEMBL17846438 | 0.77 | EPHX2 (0.58) | ME3EPHX2KMT2ASMN1; SMN2SMYD3 | |
| SCHEMBL7091382 | 0.77 | ME3 (0.59) | ME3EPHX2SMN1; SMN2CHRM4NPC1 | |
| SCHEMBL25680457 | 0.77 | EPHX2 (0.54) | MTNR1AMTNR1BME3EPHX2SMN1; SMN2 | |
| SCHEMBL19652146 | 0.77 | CKS1B (0.59) | ME3EPHX2SMN1; SMN2NPY5RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155227-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | Dickson, Suzanne L (SE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009020419-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | DICKSON SUZANNE L (SE) | 2009-02-12 | — | — | WO | disclosed |