Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780027 | 0.81 | TAS1R3 (0.36) | — | |
| SCHEMBL2651814 | 0.79 | HPGD (0.46) | LMNASTK17B | |
| SCHEMBL6520589 | 0.78 | CYP4F2 (0.42) | LMNASTK17B | |
| SCHEMBL13356386 | 0.77 | DAO (0.40) | MAOAMAOBLMNA | |
| SCHEMBL8372279 | 0.76 | TRPA1 (0.39) | LMNA | |
| SCHEMBL2646898 | 0.76 | ALDH1A1 (0.53) | LMNA | |
| SCHEMBL1555918 | 0.75 | MAPT (0.40) | MAOAMAOB | |
| SCHEMBL14884688 | 0.75 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL1575406 | 0.75 | KDM4E (0.42) | LMNASTK17B | |
| SCHEMBL31451660 | 0.74 | SLC6A4 (0.35) | LMNASTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103429-A1 | 1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists | PFIZER INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010103429-A1 | 1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists | PFIZER INC. (US) | 2010-09-16 | — | — | WO | disclosed |