Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812643 | 0.92 | IDH1 (0.35) | DAOGPR52GRIK1IDH1 | |
| SCHEMBL28133636 | 0.84 | GRIK1 (0.46) | GPR52GRIK1SMN1; SMN2FFAR1 | |
| SCHEMBL27791502 | 0.79 | CTSL (0.37) | GRIK1 | |
| SCHEMBL28159929 | 0.78 | ALDH1A1 (0.36) | GPR52SMN1; SMN2 | |
| SCHEMBL28847179 | 0.72 | GPR52 (0.43) | GPR52GRIK1FFAR1 | |
| SCHEMBL28159928 | 0.72 | GRIK1 (0.37) | GRIK1SMN1; SMN2 | |
| SCHEMBL28847240 | 0.71 | CTBP2 (0.47) | GPR52 | |
| SCHEMBL28159931 | 0.70 | GPR52 (0.47) | GPR52FFAR1 | |
| SCHEMBL28129210 | 0.69 | FFAR1 (0.44) | GPR52SMN1; SMN2FFAR1 | |
| SCHEMBL27833451 | 0.69 | TRPV1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101820760-A | Condensed hetero ring | SEPRACOR INC | 2010-09-01 | — | — | CN | disclosed |