Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815172 | 0.80 | ALDH1A1 (0.33) | BRD4CREBBPKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27770942 | 0.77 | L3MBTL1 (0.46) | BRD4CREBBPKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28801679 | 0.76 | TDP1 (0.35) | BRD4CREBBPKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27792032 | 0.76 | MEN1 (0.36) | BRD4CREBBPKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28411992 | 0.63 | MAOB (0.45) | CREBBPALDH1A1L3MBTL1MAPTFFAR1 | |
| SCHEMBL28992050 | 0.62 | MEN1 (0.37) | CREBBPS1PR5FFAR1 | |
| SCHEMBL28991825 | 0.62 | MEN1 (0.37) | CREBBPALDH1A1HPGDS1PR5FFAR1 | |
| SCHEMBL11354689 | 0.61 | PTGER1 (0.47) | BRD4PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28469694 | 0.61 | CES1 (0.50) | ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL13437541 | 0.59 | BRD4 (0.35) | BRD4CREBBPKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101636379-A | Amine derivatives and their use in beta-2-adrenoreceptor mediated diseases | ASTRAZENECA AB | 2010-01-27 | — | — | CN | disclosed |