Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13649195 | 0.81 | GAA (0.37) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL30183188 | 0.79 | SMN1; SMN2 (0.51) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12804219 | 0.77 | MAPT (0.42) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29696309 | 0.75 | LMNA (0.53) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL19954279 | 0.75 | LMNA (0.53) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL4922867 | 0.74 | GRIA1 (0.44) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL29559680 | 0.74 | KDM4E (0.40) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL12805020 | 0.74 | KDM4E (0.40) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL23207522 | 0.72 | KDM4E (0.62) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL17035908 | 0.72 | ADRB1 (0.60) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101827847-A | Purine derivatives as adenosine al receptor ligands | NOVARTIS AG | 2010-09-08 | — | — | CN | disclosed |