Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19954279 | 1.00 | LMNA (0.53) | LMNAKMT2AKDM4EALDH1A1HCRTR1 | |
| SCHEMBL13990481 | 0.83 | LMNA (0.53) | LMNAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL3462062 | 0.77 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL28987735 | 0.77 | ADORA2A (0.43) | LMNAKMT2AKDM4EALDH1A1HCRTR1 | |
| SCHEMBL27150414 | 0.77 | ADRB1 (0.49) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10688400 | 0.77 | NOTUM (0.50) | LMNAKDM4EALDH1A1FAAHL3MBTL1 | |
| SCHEMBL21851483 | 0.76 | LMNA (0.46) | LMNAKMT2AKDM4EALDH1A1HCRTR1 | |
| SCHEMBL27792203 | 0.75 | MAPT (0.45) | LMNAKMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL3318259 | 0.75 | NOTUM (0.58) | KDM4EALDH1A1MAPTCHRNA7 | |
| SCHEMBL2728318 | 0.74 | LMNA (0.57) | LMNAKMT2AKDM4EALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003986-A1 | INHIBITOR COMPOUNDS | Cincera Therapeutics Pty Ltd (AU) | 2022-06-01 | — | — | EP | disclosed |