Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15203036 | 0.76 | CRHBP (0.58) | CES2CES1HSD17B10TSHRMAPT | |
| SCHEMBL1514401 | 0.76 | CRHBP (0.58) | CES2CES1HSD17B10TSHRMAPT | |
| SCHEMBL27792948 | 0.76 | TSHR (0.45) | HSD17B10TSHRMAPTMEN1KMT2A | |
| SCHEMBL27814220 | 0.74 | ALDH1A1 (0.51) | HSD17B10MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7190826 | 0.74 | TSHR (0.64) | CES2CES1HSD17B10TSHRMAPT | |
| SCHEMBL14747794 | 0.73 | PTGS1 (0.60) | TSHRLMNACYP3A4PTGS2 | |
| SCHEMBL17117159 | 0.72 | TSHR (0.62) | CES2CES1HSD17B10TSHRMAPT | |
| SCHEMBL5945870 | 0.71 | SMN1; SMN2 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27792940 | 0.70 | S100A4 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27793005 | 0.70 | MAPT (0.46) | TSHRMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817774-B | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2012-03-21 | — | — | CN | disclosed |
| CN-101817774-A | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2010-09-01 | — | — | CN | disclosed |