Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | RGS4 | P49798 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29099282 | 0.98 | SIGMAR1 (0.38) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| SCHEMBL25379874 | 0.79 | LMNA (0.41) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| SCHEMBL8804597 | 0.79 | SIGMAR1 (0.39) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| Bromide SCHEMBL28711468 | 0.76 | SIGMAR1 (0.37) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| SCHEMBL11048801 | 0.76 | SIGMAR1 (0.41) | SIGMAR1GSK3AGSK3BMGLLMC4R | |
| SCHEMBL5174444 | 0.75 | SIGMAR1 (0.36) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| SCHEMBL30631716 | 0.75 | SIGMAR1 (0.36) | SIGMAR1GSK3AGSK3BMGLLMC4R | |
| SCHEMBL23036031 | 0.75 | LMNA (0.42) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| SCHEMBL10619250 | 0.75 | SIGMAR1 (0.36) | SIGMAR1GSK3AGSK3BMGLLF2 | |
| Bromide SCHEMBL29099281 | 0.73 | SIGMAR1 (0.41) | SIGMAR1MC4RPOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863911-A | A process for preparing 1-R1-3, 4-dehydro-3 or 4-R6-piperidine | SHANGHAI AQ BIO PHARMA CO LTD | 2010-10-20 | — | — | CN | disclosed |