Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL28854308 | 0.93 | SIGMAR1 (0.36) | SIGMAR1LOXL2MC4ROPRL1HTR2A | |
| SCHEMBL8804597 | 0.79 | SIGMAR1 (0.39) | SIGMAR1LOXL2MC4RCYP2A6HTR2A | |
| SCHEMBL25379874 | 0.76 | LMNA (0.41) | SIGMAR1MC4RSMN1; SMN2LMNAPOLB | |
| Bromide SCHEMBL29099282 | 0.75 | SIGMAR1 (0.38) | SIGMAR1MC4RDRD4LMNAPOLB | |
| SCHEMBL28790693 | 0.74 | ALDH1A1 (0.41) | SIGMAR1MC4RSMN1; SMN2DRD4LMNA | |
| Bromide SCHEMBL28711468 | 0.73 | SIGMAR1 (0.37) | SIGMAR1MC4RDRD4LMNAGSK3A | |
| SCHEMBL5969762 | 0.73 | ADRA1D (0.38) | — | |
| SCHEMBL9817613 | 0.72 | CYP2D6 (0.38) | SIGMAR1LOXL2TAAR1DRD4 | |
| SCHEMBL10619250 | 0.72 | SIGMAR1 (0.36) | SIGMAR1MC4RGSK3AGSK3BMGLL | |
| SCHEMBL5174444 | 0.72 | SIGMAR1 (0.36) | SIGMAR1MC4RDRD4LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442286-A | Preparation of amines by the reduction of imines with phosphorous acid | PETROLITE CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |