Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27814919 | 0.94 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL18166533 | 0.84 | CYP1A2 (0.56) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL10178196 | 0.81 | ADORA2B (0.68) | PDE4APDE4BPDE4CPDE4DSMN1; SMN2 | |
| SCHEMBL10178000 | 0.79 | GAA (0.55) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| O-Xylene SCHEMBL27814994 | 0.79 | CYP1A2 (0.74) | ALDH1A1CYP1A2MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL10178118 | 0.78 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL18166542 | 0.78 | CYP1A2 (0.57) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| Fluorobenzene SCHEMBL27793554 | 0.77 | MAPK1 (0.63) | ALDH1A1CYP1A2MAPK1SMN1; SMN2NPSR1 | |
| Ethylbenzene SCHEMBL28785055 | 0.77 | LMNA (0.66) | ALDH1A1CYP1A2MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL10113885 | 0.77 | KMT2A (0.71) | ALDH1A1CYP1A2MAPK1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801362-B | Methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2014-01-22 | — | — | CN | disclosed |
| CN-101801362-A | methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2010-08-11 | — | — | CN | disclosed |