Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794679 | 0.90 | MAPT (0.50) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27815872 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27815840 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27794673 | 0.84 | MAPT (0.47) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27815864 | 0.84 | AR (0.55) | MAPTHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL27815846 | 0.84 | MAPT (0.46) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL27836804 | 0.82 | MAPT (0.52) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL28788352 | 0.80 | LMNA (0.55) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL27815851 | 0.79 | MAPT (0.61) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL4196714 | 0.79 | SMN1; SMN2 (0.67) | ALDH1A1MAPTHTTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863824-A | Synthesis method of chemical compound containing a dihydrogen ferrocenylmethyl-substituted indenes ketone and pyrrole skeleton | GUANGZHOU INST BIOMED & HEALTH | 2010-10-20 | — | — | CN | disclosed |