Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | XBP1 | P17861 | 2/20 | 0.67 |
| ▸ | TDP2 | O95551 | 2/20 | 0.67 |
| ▸ | NSD2 | O96028 | 2/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GALK1 | P51570 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815872 | 0.89 | ALDH1A1 (0.54) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27794679 | 0.81 | MAPT (0.50) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27794665 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27794667 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL28788352 | 0.76 | LMNA (0.55) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27794673 | 0.76 | MAPT (0.47) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27815864 | 0.76 | AR (0.55) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27815840 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27815846 | 0.76 | MAPT (0.46) | SMN1; SMN2MAPTLMNAXBP1TDP2 | |
| SCHEMBL27815851 | 0.75 | MAPT (0.61) | SMN1; SMN2MAPTLMNAXBP1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036441-A1 | Indole Derivatives With Antitumor Activity | CELL THERAPEUTICS EUROPE S.R.L. (IT) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036441-A1 | Indole Derivatives With Antitumor Activity | IDO1, IDO2, INMT | SMN1; SMN2 4350/4885MAPT 2732/4885LMNA 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.