Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | XBP1 | P17861 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP2 | O95551 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GALK1 | P51570 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794679 | 0.93 | MAPT (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27794665 | 0.89 | ALDH1A1 (0.58) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL4196714 | 0.89 | SMN1; SMN2 (0.67) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27794673 | 0.87 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27815840 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27815846 | 0.86 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27815864 | 0.86 | AR (0.55) | MAPTSMN1; SMN2LMNAXBP1NPC1 | |
| SCHEMBL27794667 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL28788352 | 0.85 | LMNA (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 | |
| SCHEMBL27815851 | 0.84 | MAPT (0.61) | ALDH1A1MAPTSMN1; SMN2LMNAXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102140096-A | Synthesis method of nitrogen-containing heterocyclic compound | GUANGZHOU INST BIOMED & HEALTH | 2011-08-03 | — | — | CN | disclosed |
| CN-101863824-A | Synthesis method of chemical compound containing a dihydrogen ferrocenylmethyl-substituted indenes ketone and pyrrole skeleton | GUANGZHOU INST BIOMED & HEALTH | 2010-10-20 | — | — | CN | disclosed |