Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456951 | 0.78 | LDHA (0.46) | VNN1KDM5AKDM5BKDM4CMEN1 | |
| SCHEMBL9485705 | 0.75 | NPC1 (0.49) | KDM4EALDH1A1HPGDHSD17B10HTR2C | |
| SCHEMBL24230227 | 0.75 | TSHR (0.67) | ALDH1A1HPGDATMPTPN1LPAR1 | |
| SCHEMBL15737161 | 0.73 | NR4A2 (0.49) | VNN1ALKBH1HTR2CHTR2BKDM5A | |
| SCHEMBL11828345 | 0.73 | RXRA (0.53) | KDM4EATMKDM5AKDM5BKDM4A | |
| SCHEMBL4677195 | 0.73 | GCK (0.59) | VNN1RARARARBRARGGCK | |
| SCHEMBL4636142 | 0.73 | DHODH (0.48) | VNN1HPGDKDM5AKDM5BKDM4C | |
| SCHEMBL3226195 | 0.72 | NR4A2 (0.54) | ALKBH1HTR2CHTR2BKDM5AKDM5B | |
| SCHEMBL20894099 | 0.71 | NPC1 (0.45) | VNN1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29631019 | 0.71 | NPC1 (0.45) | VNN1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646656-A | Pyrimidine hydrazide compounds as the PGDS inhibitor | SANOFI AVENTIS FR | 2010-02-10 | — | — | CN | claimed |
| CN-101646656-B | Pyrimidine hydrazide compounds as PGDS inhibitors | SANOFI AVENTIS SPA | 2013-08-14 | — | — | CN | disclosed |
| CN-101646656-A | Pyrimidine hydrazide compounds as the PGDS inhibitor | SANOFI AVENTIS FR | 2010-02-10 | — | — | CN | disclosed |