Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760544 | 0.86 | LTA4H (0.52) | LTA4HKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27961825 | 0.83 | HAO1 (0.51) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL177968 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL16838784 | 0.83 | HAO1 (0.47) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL21525575 | 0.81 | CA1 (0.59) | KDM4EHTTRAB9ANPC1LMNA | |
| SCHEMBL3816388 | 0.79 | NNMT (0.48) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL29525223 | 0.79 | NNMT (0.48) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL16838765 | 0.79 | LMNA (0.59) | KDM4EHTTRAB9ANPSR1LMNA | |
| SCHEMBL27368615 | 0.79 | OPRM1 (0.46) | KDM4EALDH1A1MEN1KMT2ABRCA1 | |
| SCHEMBL8306130 | 0.78 | KDM4E (0.53) | LTA4HKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201261-A | Lactam derivatives as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-07-10 | — | — | CN | disclosed |
| CN-101842357-A | Substituted pyrazole derivatives | TAKEDA PHARMACEUTICAL | 2010-09-22 | — | — | CN | disclosed |