Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865101 | 0.83 | RXRA (0.53) | RXRARXRBRXRGPTPN5MAOA | |
| SCHEMBL1538533 | 0.82 | TSHR (0.59) | RXRARXRBRXRGTSHRPTPN5 | |
| SCHEMBL611807 | 0.82 | RXRA (0.67) | RXRARXRBRXRGPTPN5MAOA | |
| SCHEMBL29681626 | 0.82 | RXRA (0.67) | RXRARXRBRXRGPTPN5MAOA | |
| SCHEMBL8897762 | 0.81 | PGK1 (0.44) | TSHRPTGS2ALDH1A1 | |
| SCHEMBL14188565 | 0.80 | RXRA (0.65) | RXRARXRBRXRGPTPN5MAOA | |
| SCHEMBL8750479 | 0.79 | PTGS2 (0.54) | TSHRPTGS2ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL7374037 | 0.78 | RXRA (0.44) | RXRARXRBRXRGTSHRPTPN5 | |
| SCHEMBL1252080 | 0.78 | RXRA (0.49) | RXRARXRBRXRGPTPN5MAOA | |
| SCHEMBL7669035 | 0.78 | RXRA (0.49) | RXRARXRBRXRGPTPN5MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101918386-B | 4-phenylpyrane-3,5-diones, 4-phenylthiopyrane-3,5-diones and 2-phenylcyclohexane-1,3,5-triones as herbicides | SYNGENTA LTD | 2013-11-13 | — | — | CN | disclosed |
| CN-101679177-B | Herbicidally active bicyclic 1,3-dione compounds | SYNGENTA LTD | 2013-08-21 | — | — | CN | disclosed |
| CN-103180300-A | Process for producing pyridazinone compound and intermediate thereof | SUMITOMO CHEMICAL CO | 2013-06-26 | — | — | CN | disclosed |
| CN-101918386-A | As the 4-phenylpyran-3 of weedicide, 5-diketone, 4-phenyl thiapyran-3,5-diketone and 2-phenyl hexamethylene-1,3,5-triketone | SYNGENTA LTD | 2010-12-15 | — | — | CN | disclosed |
| CN-101679177-A | Two rings 1 of weeding activity, the 3-dione compounds | SYNGENTA LTD | 2010-03-24 | — | — | CN | disclosed |