Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.44 |
| ▸ | PGK2 | P07205 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750604 | 0.85 | ACHE (0.50) | MAPTSMN1; SMN2ALDH1A1TP53CYP3A4 | |
| SCHEMBL8094299 | 0.85 | PNMT (0.45) | TSHRALDH1A1HPGDADRB1 | |
| SCHEMBL30549338 | 0.85 | PNMT (0.45) | TSHRALDH1A1HPGDADRB1 | |
| SCHEMBL22926647 | 0.84 | HDAC4 (0.53) | PGK1PGK2TSHRHDAC4HDAC8 | |
| SCHEMBL38663914 | 0.83 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL931961 | 0.83 | ACHE (0.44) | HDAC4SMN1; SMN2 | |
| SCHEMBL28744749 | 0.83 | ADRB1 (0.57) | TSHRKDM4EALDH1A1CA2CYP3A4 | |
| SCHEMBL212526 | 0.83 | ACHE (0.44) | HDAC4SMN1; SMN2 | |
| SCHEMBL30058998 | 0.83 | ACHE (0.44) | HDAC4SMN1; SMN2 | |
| SCHEMBL5843001 | 0.83 | PGK1 (0.38) | PGK1PGK2TSHRHDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150001178-A1 | MONOMER FOR HARDMASK COMPOSITION AND HARDMASK COMPOSITION INCLUDING THE MONOMER AND METHOD OF FORMING PATTERNS USING THE HARDMASK COMPOSITION | CHEIL INDUSTRIES, INC. (KR) | 2015-01-01 | — | — | US | disclosed |
| EP-0531715-B1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5426237-A | Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| EP-0531715-A1 | Process for producing alcohols and ketones | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0071833-B1 | PROCESS FOR PRODUCING 4-BENZOYLPYRAZOLES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-02-04 | — | — | EP | disclosed |
| US-4560814-A | Process for alkylating halogenated and trifluoromethylated benzene compounds | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-12-24 | — | — | US | disclosed |
| US-4415739-A | Process for producing 4-benzoylpyrazoles | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0071833-A1 | Process for producing 4-benzoylpyrazoles | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-3968138-A | HERBICIDE | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
| US-3939084-A | Functional fluid compositions containing substituted pyrimidines | MONSANTO COMPANY (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150001178-A1 | MONOMER FOR HARDMASK COMPOSITION AND HARDMASK COMPOSITION INCLUDING THE MONOMER AND METHOD OF FORMING PATTERNS USING THE HARDMASK COMPOSITION | ARCN1, DDRGK1, ACTN1 | PGK1 241/4885PGK2 465/4885TSHR 4713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.