SCHEMBL2779568

SCHEMBL2779568

Cc1sccc1Nc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
HSD17B10 Q99714 5/20 0.44
MAPT P10636 7/20 0.43
GAA P10253 6/20 0.43
TDP1 Q9NUW8 5/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
KDM4E B2RXH2 2/20 0.43
RECQL P46063 2/20 0.43
GLA P06280 1/20 0.43
ALDH1A1 P00352 7/20 0.43
RAB9A P51151 3/20 0.43
ALOX15 P16050 5/20 0.42
TSHR P16473 4/20 0.42
MAPK1 P28482 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
ALOX12 P18054 2/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16389428 0.75 HSD17B10 (0.44) HPGDHSD17B10MAPTGAATDP1
SCHEMBL15399737 0.71 NPSR1 (0.39) HPGDHSD17B10MAPTGAATDP1
SCHEMBL11350331 0.71 PTPN2 (0.56) HPGDHSD17B10MAPTGAAKMT2A
SCHEMBL12666514 0.70
SCHEMBL5804880 0.70 LMNA (0.68) HPGDMAPTKMT2AMEN1KDM4E
SCHEMBL10573557 0.70 CA2 (0.44) MAPTGAATDP1KMT2AMEN1
SCHEMBL6821232 0.69 MAPT (0.44) HPGDHSD17B10MAPTGAATDP1
SCHEMBL444976 0.69 MAPT (0.70) HPGDHSD17B10MAPTGAATDP1
SCHEMBL1712834 0.69 GAA (0.55) HPGDHSD17B10MAPTGAATDP1
SCHEMBL304152 0.69 MAPT (0.56) HPGDHSD17B10MAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2129788-B1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS LLC (US) 2014-09-03 EP disclosed
US-8642014-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2014-02-04 US disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed
EP-2129788-A2 LUMINESCENT COMPOUNDS Seta Biomedicals, LLC (US) 2009-12-09 EP disclosed
WO-2008094637-A2 LUMINESCENT COMPOUNDS SETA BIOMEDICALS. LLC (US) 2008-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100266507-A1 LUMINESCENT COMPOUNDS SQLE, COASY, ZKSCAN2 HPGD 3318/4885HSD17B10 622/4885MAPT 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.