Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986795 | 0.82 | MAPT (0.59) | ALDH1A1ATML3MBTL1LMNAMAPT | |
| SCHEMBL543681 | 0.80 | — | — | |
| SCHEMBL25060916 | 0.78 | — | — | |
| SCHEMBL157088 | 0.77 | — | — | |
| SCHEMBL8570864 | 0.76 | — | — | |
| SCHEMBL2859096 | 0.74 | LMNA (0.73) | ALDH1A1ATML3MBTL1LMNAMAPT | |
| SCHEMBL7074946 | 0.74 | LMNA (0.72) | ALDH1A1ATML3MBTL1LMNAMAPT | |
| SCHEMBL27816725 | 0.73 | LMNA (0.46) | ALDH1A1ATML3MBTL1LMNAMAPT | |
| SCHEMBL19475102 | 0.72 | ALDH1A1 (0.55) | ALDH1A1ATML3MBTL1LMNAMAPT | |
| SCHEMBL9911456 | 0.72 | TP53 (0.56) | ALDH1A1ATML3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102174029-A | Di(5-methyl-1,2,3-thiadiazole-4-formoxyl urea) compounds, and preparation method and application thereof | UNIV NANKAI | 2011-09-07 | — | — | CN | claimed |
| CN-101863856-A | Bi(4-methyl-1,2,3-thiadiazole-5-phenurone) compounds and preparation method and application thereof | LIER CHEMICAL CO LTD | 2010-10-20 | — | — | CN | claimed |
| CN-102174029-A | Di(5-methyl-1,2,3-thiadiazole-4-formoxyl urea) compounds, and preparation method and application thereof | UNIV NANKAI | 2011-09-07 | — | — | CN | disclosed |
| CN-101863856-A | Bi(4-methyl-1,2,3-thiadiazole-5-phenurone) compounds and preparation method and application thereof | LIER CHEMICAL CO LTD | 2010-10-20 | — | — | CN | disclosed |