SCHEMBL7074946

SCHEMBL7074946

Nc1ccc(NC(=O)c2csnn2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.72
ALDH1A1 P00352 5/20 0.71
TP53 P04637 4/20 0.71
POLB P06746 2/20 0.71
RAB9A P51151 2/20 0.71
NPC1 O15118 1/20 0.71
HPGD P15428 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
MAPT P10636 8/20 0.69
THRB P10828 2/20 0.60
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
PKM P14618 1/20 0.51
APEX1 P27695 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GFER P55789 1/20 0.50
MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2859096 0.85 LMNA (0.73) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL7081543 0.83 LMNA (0.67) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL15707393 0.83 LMNA (0.70) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6815505 0.81 THRB (0.61) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6816147 0.81 ALDH1A1 (0.80) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6814421 0.81 ALDH1A1 (0.80) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6814682 0.80 ALDH1A1 (0.79) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6816159 0.79 THRB (0.58) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6815363 0.79 LMNA (0.65) LMNAALDH1A1TP53POLBRAB9A
SCHEMBL6815493 0.78 LMNA (0.63) LMNAALDH1A1TP53POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725998-B Ultra-fine circuit film stripping liquid and preparation method thereof 深圳市天熙科技开发有限公司 2025-02-11 CN claimed
CN-118725998-A Ultra-fine circuit film stripping liquid and preparation method thereof 深圳市天熙科技开发有限公司 2024-10-01 CN claimed
CN-118725998-B Ultra-fine circuit film stripping liquid and preparation method thereof 深圳市天熙科技开发有限公司 2025-02-11 CN disclosed
CN-118725998-A Ultra-fine circuit film stripping liquid and preparation method thereof 深圳市天熙科技开发有限公司 2024-10-01 CN disclosed
US-6555561-B2 N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus WYETH 2003-04-29 US disclosed
US-20030036653-A1 Diaminopyridine-containing thiourea inhibitors of herpes viruses AMERICAN HOME PRODUCTS CORPORATION 2003-02-20 US disclosed
US-6407123-B1 VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS AMERICAN HOME PRODUCTS CORPORATION 2002-06-18 US disclosed
US-6403617-B1 INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMANHERPESVIRUSES-6 AND -7, AND KAPOSI HERPESVIRUS AMERICAN HOME PRODUCTS CORP. 2002-06-11 US disclosed
US-20020026055-A1 Aminopyridine-containing thiourea inhibitors of herpes viruses AMERICAN HOME PRODUCTS CORPORATION 2002-02-28 US disclosed
US-20010039348-A1 Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group AMERICAN HOME PRODUCTS CORPORATION (US) 2001-11-08 US disclosed
US-6197803-B1 VIRICIDES; PREVENTION REPRODUCTION AMERICAN HOME PRODUCTS CORPORATION 2001-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036653-A1 Diaminopyridine-containing thiourea inhibitors of herpes viruses HAVCR2, CCR6, CXCR6 LMNA 4701/4885ALDH1A1 3447/4885TP53 1750/4885
US-20010039348-A1 Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group CCR6, HAVCR2, BCOR LMNA 4433/4885ALDH1A1 3620/4885TP53 1486/4885
US-20020026055-A1 Aminopyridine-containing thiourea inhibitors of herpes viruses TK1, TPMT, CXCR6 LMNA 4692/4885ALDH1A1 3601/4885TP53 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.