Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160668 | 0.66 | HSD17B10 (0.47) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL27614341 | 0.65 | POLB (0.48) | HSD17B10MAPK1MEN1KMT2AMAPT | |
| SCHEMBL14837406 | 0.65 | PARP1 (0.52) | HSD17B10ALOX15CASP1CASP7LMNA | |
| SCHEMBL16739249 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL35787 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL8708889 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL35972 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL919063 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL5459284 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 | |
| SCHEMBL4556902 | 0.65 | HSD17B10 (0.46) | HSD17B10ALOX15MAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1968929-B | Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof, and use of the same as medicaments | SANOFI AVENTIS DEUTSCHLAND | 2010-09-08 | — | — | CN | disclosed |